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depakote
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Depakote

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Depakote Uses Depakote (divalproex sodium), in both delayed-release tablet and capsule form, is used to treat certain types of seizures and convulsions. It may be prescribed alone or with other epilepsy medications. The delayed-release tablets are also used to control the manic episodes--periods of abnormally high spirits and energy--that occur in bipolar disorder (manic depression). An extended-release form of this drug, Depakote ER, is prescribed to prevent migraine headaches. The delayed-release tablets are also used for this purpose. Depakote How To Take Take the tablet with water and swallow it whole (don't chew it or crush it). It has a special coating to avoid upsetting your stomach. If you are taking the sprinkle capsule, you can swallow it whole or open it and sprinkle the contents on a teaspoon of soft food such as applesauce or pudding. Swallow it immediately, without chewing. The sprinkle capsules are large enough to be opened easily. Depakote can be taken with meals or snacks to avoid stomach upset. Take it exactly as prescribed. Depakote Side Effects Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Because Depakote is often used with other antiseizure drugs, it may not be possible to determine whether a side effect is due to Depakote alone. Only your doctor can determine if it is safe for you to continue taking Depakote. More common side effects may include: Abdominal pain, abnormal thinking, breathing difficulty, bronchitis, bruising, constipation, depression, diarrhea, dizziness, emotional changeability, fever, flu symptoms, hair loss, headache, incoordination, indigestion, infection, insomnia, loss of appetite, memory loss, nasal inflammation, nausea, nervousness, ringing in the ears, sleepiness, sore throat, tremor, vision problems, vomiting, weakness, weight loss or gain Less common or rare side effects may include: Abnormal dreams, abnormal milk secretion, abnormal walk, aggression, anemia, anxiety, back pain, behavior problems, belching, bleeding, blood disorders, bone pain, breast enlargement, chest pain, chills, coma, confusion, coughing up blood, dental abscess, drowsiness, dry skin, ear inflammation, excessive urination (mainly children) or other urination problems, eye problems, feeling of illness, gas, growth failure in children, hallucinations, hearing problems, heart palpitations, high blood pressure, hostility, increased appetite, increased cough, involuntary rapid movement of eyeball, irregular or painful menstruation, itching, jerky movements, joint pain, lack of muscular coordination, leg cramps, liver problems, loss of bladder or bowel control, muscle or joint pain, muscle weakness, muscle pain, neck pain, nosebleed, overactivity, pneumonia, rapid heartbeat, rickets (mainly children), sedation, seeing "spots before your eyes", sensitivity to light, sinus inflammation, skin eruptions or peeling, skin rash, speech difficulties, stomach and intestinal disorders, swelling of arms and legs due to fluid retention, swollen glands, taste changes, tingling or pins and needles, twitching, urinary problems, vertigo, vision problems Depakote Medical Precautions Depakote can cause serious or even fatal liver damage, especially during the first 6 months of treatment. Children under 2 years of age are the most vulnerable, especially if they are also taking other anticonvulsant medicines and have certain other disorders such as mental retardation. The risk of liver damage decreases with age,

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but you should always be alert for the following symptoms: loss of seizure control, weakness, dizziness, drowsiness, a general feeling of ill health, facial swelling, loss of appetite, vomiting, and yellowing of the skin and eyes. If you suspect a liver problem, call your doctor immediately. Depakote has also been known to cause life-threatening damage to the pancreas. This problem can surface at any time, even after years of treatment. Call your doctor immediately if you develop any of the following warning signs: abdominal pain, loss of appetite, nausea, or vomiting. Depakote may produce birth defects if it is taken during pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Depakote appears in breast milk and could affect a nursing infant. If Depakote is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished. Depakote Drug Interactions Depakote depresses activity of the central nervous system, and may increase the effects of alcohol. Do not drink alcohol while taking this medication. If Depakote is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Depakote with the following: Amitriptyline (Elavil) Aspirin Barbiturates such as phenobarbital and Seconal Blood thinners such as Coumadin Cyclosporine (Sandimmune, Neoral) Notriptyline (Pamelor) Oral contraceptives Other seizure medications, including carbamazepine (Tegretol), clonazepam (Klonopin), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), phenytoin (Dilantin), and Primidone (Mysoline) Rifampin (Rifater) Sleep aids such as Halcion Tolbutamide (Orinase) Tranquilizers such as Valium and Xanax Zidovudine (Retrovir) Depakote Medical Notes You should not take this medication if you have liver disease or your liver is not functioning well, or if you have a genetic abnormality known as urea cycle disorder (UCD). If you are sensitive to or have ever had an allergic reaction to Depakote, you should not take this medication. Depakote Missed Dosages If you take Depakote once a day, take your dose as soon as you remember. If you don't remember until the next day, skip the missed dose and return to your regular schedule. Never take 2 doses at the same time. If you take more than one dose a day, take your dose right away if it's within 6 hours of the scheduled time, and take the rest of the day's doses at equal intervals during the day. Never take 2 doses at the same time. Depakote Storage Store at room temperature.







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